鄢德洪
鄢德洪
  • 职称:
    副研究员
  • 联系方式:
    13570351736
  • 个人网页:
  • 座右铭:
个人简介

博士生导师,国家自然科学基金面上、青年项目评审专家,深圳市后备级领军人才。在国际著名学术期刊Journal of Experimental Medicine等杂志发表论文28篇,申请发明专利5项,其中授权1项。主持承担了国家自然科学基金面上项目、国家自然科学基金青年项目、中国博士后基金、广东省自然科学基金面上项目及深圳市基础研究面上项目等15项科研项目。

研究领域

从事髓系细胞(MDSC、Macrophage)在癌症中的基础与转化研究

代表论著

1) Hafiza Kashaf Tariq, Zihao Liang , Lawan Rabiu, Abdulrahman Ibrahim , Nada Mohamady Farouk Abdalsalam, Rong Li, Qiong Yang†, Xiaochun Wan*,†, Dehong Yan *,†. Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy. Cells. 2025 Jan 13; 14(02): 108.

2) Nada Mohamady Farouk Abdalsalam, Abdulrahman Ibrahim, Muhammad Auwal Saliu, Tzu-Ming Liu*, Xiaochun Wan *, Dehong Yan *. MDSC: a new potential breakthrough in CAR-T therapy for solid tumors. Cell Communication and Signaling. 2024 Dec 19;22(1):612.

3)Nada Mohamady Farouk Abdalsalam, Zihao Liang, Hafiza Kashaf Tariq, Abdulrahman Ibrahim, Rong Li, Xiaochun Wan*, Dehong Yan*. Etomoxir Sodium Salt Promotes Imidazole Ketone Erastin-Induced Myeloid-Derived Suppressor Cell Ferroptosis and Enhances Cancer Therapy. Biology (Basel). 2024 Nov 19;13(11):949.

4)Zihao Liang, Zixin Chen, Jinwei Chen, Yunfan Zhou, Hua Chen, Meimei Gu, Dehong Yan*, Qiong Yang*. IRF3 Promotes Asthma Pathogenesis by Regulating Type 2 Innate Lymphoid Cells. Immunological Investigations. 2024 Oct 29:1-14. 5) Dehong Yan, Jinghui Wang, Honghong Sun, Ali Zamani, Honglin Zhang, Weihong Chen, Aifa Tang, Qingguo Ruan, Xiaolu Yang, Youhai H. Chen*, Xiaochun Wan*. TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. Journal of Experimental Medicine. 2020 Feb 3; 217(2): e20182005.

科研\学术成果

2018、2019、2021年先后三次获美国免疫学会AAI旅行奖、AAI早期学术教师奖