Aldo Tagliabue
Aldo Tagliabue首席科学家、教授
  • 职称：
    研究员
  • 联系方式：
    aldo.tagliabue@itb.cnr.it
  • 个人网页：
  • 座右铭：
个人简介

中国科学院深圳先进技术研究院研究员，炎症与疫苗研究室首席科学家，曾任意大利国家研究院的高级科学家，意大利Achilles Vaccines（阿基里斯疫苗公司）的联合创始人，ALTA srl.科研咨询公司的创始人。2021 年入选教育部“长江学者奖励计划”讲席学者项目。

研究领域

人体免疫学研究以应对传染性疾病的预防与治疗。人用疫苗（针对伤寒沙门氏菌、百日咳博德氏菌、B型脑膜炎球菌）和疫苗佐剂（MF59）的研发，相关疫苗与佐剂以上市供大众注射、使用。人用抗COVID-19单克隆抗体的鉴定和临床应用。相关新冠中和抗体已获批进入1期临床实验。

代表论著

1. Tagliabue, A., & Rappuoli, R. (2018). Changing Priorities in Vaccinology: Antibiotic Resistance Moving to the Top. Frontiers in immunology, 9, 1068.

2. Boraschi, D., & Tagliabue, A. (2013). The interleukin-1 receptor family. Seminars in immunology, 25(6), 394–407.

3. Tagliabue, A., & Rappuoli, R. (2008). Vaccine adjuvants: the dream becomes real. Human vaccines, 4(5), 347-349.

4. Tagliabue, A., Befus, A. D., Clark, D. A., & Bienenstock, J. (1982). Characteristics of natural killer cells in the murine intestinal epithelium and lamina propria. Journal of Experimental Medicine, 155(6), 1785-1796.

5. Tagliabue, A., Nencioni, L., Villa, L., Keren, D. F., Lowell, G. H., & Boraschi, D. (1983). Antibody-dependent cell-mediated antibacterial activity of intestinal lymphocytes with secretory IgA. Nature, 306(5939), 184-186.

科研\学术成果

学术专著

1.Leite, L., Tagliabue, A., Rappuoli, R. and Yvonne, O. L.. A global perspective on vaccines: priorities, challenges and online information. Frontiers in Immunology Press, 2020.

2.Yun, C.H., Leite, L., Tagliabue, A., and Boraschi, D.. 2015. Vaccines of the future: the role of inflammation and adjuvanticity. J. Immunology Res. 2015: ID789595. http://dx.doi.org/10.1155/2015/789595

已授权发明专利

1.D. Boraschi; P. Bossù; P. Ruggiero; G. Macchia; A. Tagliabue; F. Frigerio; R. Grifantini; G. Frascotti and G. Grandi; IL-1 receptor antagonists with enhanced inhibitory activity, 1995-09-20, WIPO, PCT/EP1995/003708.

2.G. Maurizi; P. Bossu'; D. Boraschi; P. Ruggiero; A. Tagliabue; Method for the recovery of biologically active products from microorganisms, 1994-11-15, 意大利, ITMI942308A.

3.P. Ghiara; L. Villa; L. Nencioni; A. Tagliabue and D. Boraschi; Use of the tumor necrosis factor as adjuvant of the immune response, 1988-10-31, 欧洲, EP88118155.6.

4.L. Nencioni; G. Antoni; D. Boraschi and A. Tagliabue; A synthetic nonapeptide of use as an adjuvant, 1988-02-16, 欧洲, EP88830056.3.