中国科学院遗传与发育生物学研究所发育生物学博士学位(2011-2017),美国圣路易斯华盛顿大学医学院儿科系博士后(2017-2021),项目科学家(staff scientist,2021-2022),高级科学家(senior scientist,2022-2024)。中国科学院深圳先进技术研究院研究员(2024-至今),获得国家自然科学优秀青年基金项目(海外)资助。研究成果发表在Cell Stem Cell、Blood、Cell Reports、 Leukemia、Nature Plants、Blood Advances、Experimental Hematology等国际知名期刊。现为美国血液学协会会员和广东省抗癌协会肿瘤代谢专业委员会委员。
血细胞发育和白血病发生的分子调控机制
Y Li, J Mendoza, R Patel, E Casey, E Denby, D Bryder, J Magee. LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression. Leukemia, 2024, 38: 648-651
Y Li, W Yang, H Wang, R Patel, E Casey, E Denby, J Magee. Basal type I interferon signaling has only modest effects on neonatal and juvenile hematopoiesis. Blood Advances, 2023, 7 (11): 2609–2621
Y Li, W Yang, H Wang, R Patel, E Casey, E Denby, J Magee. FLT3ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation. Blood, 2023, 141 (12): 1442-1456
Y Li, J Magee. Transcriptional reprogramming in neonatal hematopoietic stem and progenitor cells. Experimental Hematology, 2021, 101: 25-33.
Y Li*, W Kong*, W Yang, R Patel, E Casey, T Okeyo-Owuor, M White, S Porter, S Morris, J Magee. Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth. Cell Stem Cell, 2020, 27 (5): 732-747. *Equal contribution.