方程，中国科学院深圳先进技术研究院医药所，副研究员。2018年毕业于北京大学，获得博士学位，专业为化学生物组学。2018-2020在中国科学院深圳先进技术研究院从事博士后研究，出站后留院工作至今。目前主要研究领域为血脑屏障在脑血管和神经系统疾病发生发展中的作用、机制和靶向干预药物研发，在Proceedings of the National Academy of Sciences、Cell Reports、Journal of Neuroinflammation、Pharmacological Research、Journal of Biological Chemistry等高水平学术期刊上发表多篇论文。先后主持国自然青年项目、中国博士后基金面上资助项目、广东省科学基金-面上项目，深圳市基础研究面上项目等。

脑血管病发病机制与治疗

1. Ziying Feng#, Cheng Fang#, Min Yu#, Yueqing Wang, Femi Ogunleye, Jie Lin, Yuxiang Liu, Zhongyi Zeng, Linsheng Zeng, Zhizhun Mo, Yinzhong Ma*; Snake venom weakens neurovascular integrity and promotes vulnerability to neuroinflammation, International Immunopharmacology, 2024, 143(Pt 3):113586

2. Sen Suo#, Cheng Fang#, Wenting Liu, Qingan Liu, Zhuobo Zhang*, Junlei Chang*, Guozhong Li*; FOXM1 c.1205 C > A mutation is associated with unilateral Moyamoya disease and inhibits angiogenesis in human brain endothelial cells，Human Genetics, 2024

3. Xiaowen Huang, Pengjv Wei, Cheng Fang, Min Yu, Shilun Yang, Linhui Qiu, Yu Wang, Aimin Xu, Ruby Lai Chong Hoo, Junlei Chang*; Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia, Journal of Neuroinflammation, 2024, 21(1)

4. Hussain, Basharat#; Fang, Cheng#; Huang, Xiaowen; Feng, Ziying; Yao, Yuxuan; Wang, Yu; Chang, Junlei* ; Endothelial β-Catenin Deficiency Causes Blood-Brain Barrier Breakdown via Enhancing the Paracellular and Transcellular Permeability, Frontiers in Molecular Neuroscience , 2022, 15(895429)

5. Hussain, Basharat#; Fang, Cheng#; Chang, junlei* ; Blood–Brain Barrier Breakdown: An Emerging Biomarker of Cognitive Impairment in Normal Aging and Dementia, Frontiers in Neuroscience , 2021