易丹，中国科学院深圳先进技术研究院，副研究员。深圳市级人才，广东省青年科学家协会会员。长期从事骨与关节疾病的机制研究，研究领域包括骨缺损修复、生物材料促进骨免疫代谢、骨关节炎、强直性脊柱炎、脑骨轴平衡等。相关研究已在发表在The Innovation Medicine、Genes & Diseases、eLife、Bone Research、Annals of The Rheumatic Diseases、International Journal of Oral Science、Journal of Nanobiotechnology等杂志上；SCI检索文章23篇，文章总引用次数803，H-index：13。先后主持国家自然科学基金委青年项目、中国博士后基金面上项目和广东省基础与应用基础研究基金面上项目以及青年项目；另外作为主要骨干核心成员，参与国家自然科学基金重点项目、国际(地区)合作与交流项目、3项国家重点研发计划和香港大学RGC项目。申请中国专利及US专利多项。Bone Research、Molecular Biomedicine和Scientific Reports等杂志审稿人和JoVE杂志的客座编辑。

骨缺损修复、生物材料促进骨免疫代谢、骨关节炎、强直性脊柱炎、脑骨轴

1.Yi D; Xie R; Zeng D; Xiao J; Xiao G; Jin H; Tong L; Chen D; Loss of Axin1 in limb mesenchymal cells leads to multiple synostoses syndrome-like phenotype in mice, The Innovation Medicine, 2024, 2(1): 100053
2. Xie R#, Yi D#, Zeng D, Jie Q, Kang Q, Zhang Z, Zhang Z, Xiao G, Chen L, Tong L and Chen D. Specific deletion of Axin1 leads to activation of beta-catenin/BMP signaling resulting in fibular hemimelia phenotype in mice. eLlife. 2022;11
3.Yi D, Jin H, Lu W, Zhang C, Xiao G, Tong L and Chen D. Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice. Genes & Diseases. 2023;101147
4.Yi D, Yu H, Lu K, Ruan C, Ding C, Tong L, Zhao X and Chen D. AMPK Signaling in Energy Control, Cartilage Biology, and Osteoarthritis. Front Cell Dev Biol. 2021;9:696602
5.Zeng D, Chen Y, Liao Z, Wei G, Huang X, Liang R, Lu WW*, Yi D* and Chen Y*. Cartilage organoids and osteoarthritis research: a narrative review. Front Bioeng Biotechnol. 2023;11:1278692